Born in Athens, Greece, Zacharias studied Architecture in Aristoteles University of Thessaloniki and theater in RESAD, Madrid before turning to filmmaking. He studied scriptwriting in EICTV, Cuba and filmmaking in New York College in Athens. He is a Berlinale and Sarajevo Talent Campus alumni. He has been working as a director and scriptwriter for film and tv ever since 2006. His debut feature THE GUIDE screened in more than 20 International film festivals. His sophomore feature, DEFUNCT won the Young Jury and the Audience Award in the international competition of Thessaloniki FF and the Best Film award in KINENOVE 2020 IFF.